Catalyst-Free One-Pot Four-Component Synthesis of 3-(Imino)-pyrrolo[2,1-a]isoquinolines in Glycerol: Two Different Products through Two Different Purification Methods
The one-pot four component synthesis of 3-(Imino)-2,3-dihydropyrrolo[2,1-a]isoquinoline-1,1(10bH)-dicarbonitrile derivatives via a catalyst-free reaction between aryl aldehydes, malononitrile, isoquinoline and isocyanides was successfully conducted in glycerol as a benign, nontoxic and biodegradable promoting reaction medium. The progress of the reaction with two different common purification methods were investigated. Moreover, synthesized products were examined as chemical sensors for the detection of a wide range of metal ions and it was successful for the detection of Co2+ ions.
Jehbez, S. A., Safaei, H., & Shekouhy, M. (2020). Catalyst-Free One-Pot Four-Component Synthesis of 3-(Imino)-pyrrolo[2,1-a]isoquinolines in Glycerol: Two Different Products through Two Different Purification Methods. Organic Chemistry Research, 6(1), 13-24. doi: 10.22036/org.chem.2019.161099.1186
MLA
Seyed Ali Jehbez; Hamidreza Safaei; Mohsen Shekouhy. "Catalyst-Free One-Pot Four-Component Synthesis of 3-(Imino)-pyrrolo[2,1-a]isoquinolines in Glycerol: Two Different Products through Two Different Purification Methods". Organic Chemistry Research, 6, 1, 2020, 13-24. doi: 10.22036/org.chem.2019.161099.1186
HARVARD
Jehbez, S. A., Safaei, H., Shekouhy, M. (2020). 'Catalyst-Free One-Pot Four-Component Synthesis of 3-(Imino)-pyrrolo[2,1-a]isoquinolines in Glycerol: Two Different Products through Two Different Purification Methods', Organic Chemistry Research, 6(1), pp. 13-24. doi: 10.22036/org.chem.2019.161099.1186
VANCOUVER
Jehbez, S. A., Safaei, H., Shekouhy, M. Catalyst-Free One-Pot Four-Component Synthesis of 3-(Imino)-pyrrolo[2,1-a]isoquinolines in Glycerol: Two Different Products through Two Different Purification Methods. Organic Chemistry Research, 2020; 6(1): 13-24. doi: 10.22036/org.chem.2019.161099.1186
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