La(OTf)2-amine Grafted-GO as the First Multifunctional Catalyst for the One-pot Three-component Synthesis of α-Aminophosphonates

Document Type : Research Paper

Authors

1 Department of Chemistry, College of Sciences, University of Birjand, Birjand, Iran

2 bDepartment of Chemistry and Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Langelandsgade 140, DK-8000 Aarhus C, Denmark

Abstract

In this paper, the applicability of immobilized lanthanum (III) triflate on amine grafted graphene oxide [La(OTf)2-amine grafted-GO] as the first multifunctional catalyst is described for the efficient synthesis of α-aminophosphonates by one-pot three-component reaction of carbonyl compounds, substituted anilines and trialkyl phosphites. Various α-aminophosphonates were synthesized in good to high yields under solvent-free conditions at room temperature. The catalyst was reused five times without significant loss of its activity.

Keywords

Organic Chemistry Research
Volume 5, Issue 2
December 2019
Pages 117-127

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