An Effective Green Procedure for the Synthesis of Phenacyl Derivatives Catalyzed by Silica-bound 3-{2-[Poly(ethylene glycol)]ethyl}-substituted 1-Methyl-1H-imidazol-3-ium Bromide as a Recyclable Phase Transfer Catalyst under Aqueous Media

Ayashi, Neda; Fallah-Mehrjardi, Mehdi; Kiasat, Ali Reza

doi:10.22036/org.chem..2017.41101

An Effective Green Procedure for the Synthesis of Phenacyl Derivatives Catalyzed by Silica-bound 3-{2-[Poly(ethylene glycol)]ethyl}-substituted 1-Methyl-1H-imidazol-3-ium Bromide as a Recyclable Phase Transfer Catalyst under Aqueous Media

Document Type : Full Paper

Authors

Neda Ayashi ¹

Mehdi Fallah-Mehrjardi ²

Ali Reza Kiasat ³

¹ Chemistry Department, Collage of Science, Shahid Chamran university of Ahvaz, Ahvaz, Iran

² Department of Chemistry, Payame Noor University, Tehran, 19395-4697, Iran

³ a Chemistry Department, Collage of Science, Shahid Chamran university of Ahvaz, Ahvaz, Iran

10.22036/org.chem..2017.41101

Abstract

The use of a recyclable phase transfer catalyst, SiO2-PEG-ImBr, is demonstrated in a simple and highly efficient synthesis of phenacyl derivatives by nucleophilic substitution reaction of phenacyl halides with different anions in water. Advantages of this system are easy work-up, moderate to good yields, and recyclable catalyst. The catalyst can be recycled and reused several times with no loss of its efficiency.

Keywords

Phenacyl derivatives

Phenacyl halides

Phase transfer catalyst

Nucleophilic substitution

Silica supported