Three-component, One-pot Synthesis of Dihydropyrano[3,2-c]chromenes in Aqueous Medium in the Presence of Nano-silica Supported 1,5-Diazabicyclo(4.3.0)non-5-en
3
Departent of Organic Chemistry, Faculty of Chemistry, University of Kashan
4
Department of chemistry, Yazd University
10.22036/org.chem.2023.301814.1264
Abstract
In this research, a high efficient, simply and rapid method was applied for the synthesis of dihydropyrano[3,2-c]chromene derivatives by one-pot, three-component condensation of aldehydes, malononitrile and 4-hydroxycoumarin in H2O/ethanol (1:1 v/v) under reflux conditions. This reaction was run by using nano-silica supported 1,5-Diazabicyclo(4.3.0)non-5-en (DBN) which has been abbreviated as nano-SiO2/DBN under aqueous condition. The nano-SiO2/DBN catalyst was synthesized by reaction between silica chloride and DBN. The main advantages of this procedure are high yields, short reaction times and easy work-up. Furthermore, the catalyst could be reused for five times.
Mirjalili, B. B. F., Mehravar, M., Bamoniri, A., & Babaei, E. (2021). Three-component, One-pot Synthesis of Dihydropyrano[3,2-c]chromenes in Aqueous Medium in the Presence of Nano-silica Supported 1,5-Diazabicyclo(4.3.0)non-5-en. Organic Chemistry Research, 7(2), 127-138. doi: 10.22036/org.chem.2023.301814.1264
MLA
Bi Bi Fatemeh Mirjalili; Maryam Mehravar; Abdolhamid Bamoniri; Elaheh Babaei. "Three-component, One-pot Synthesis of Dihydropyrano[3,2-c]chromenes in Aqueous Medium in the Presence of Nano-silica Supported 1,5-Diazabicyclo(4.3.0)non-5-en". Organic Chemistry Research, 7, 2, 2021, 127-138. doi: 10.22036/org.chem.2023.301814.1264
HARVARD
Mirjalili, B. B. F., Mehravar, M., Bamoniri, A., Babaei, E. (2021). 'Three-component, One-pot Synthesis of Dihydropyrano[3,2-c]chromenes in Aqueous Medium in the Presence of Nano-silica Supported 1,5-Diazabicyclo(4.3.0)non-5-en', Organic Chemistry Research, 7(2), pp. 127-138. doi: 10.22036/org.chem.2023.301814.1264
VANCOUVER
Mirjalili, B. B. F., Mehravar, M., Bamoniri, A., Babaei, E. Three-component, One-pot Synthesis of Dihydropyrano[3,2-c]chromenes in Aqueous Medium in the Presence of Nano-silica Supported 1,5-Diazabicyclo(4.3.0)non-5-en. Organic Chemistry Research, 2021; 7(2): 127-138. doi: 10.22036/org.chem.2023.301814.1264