A Facile and Green Approach for One-Pot Synthesis of New Pyrrole Derivatives by Three-Component Reaction Between Pyrrole, Arylglyoxals and Meldrum's Acid
1
Department of Chemistry, Faculty of Science, Vali-e-Asr University of Rafsanjan, Rafsanjan 7718897111, Iran
2
Department of Chemistry, Islamic Azad University, Rafsanjan Branch, Rafsanjan, Iran
10.22036/org.chem.2023.299025.1263
Abstract
An efficient one-pot three-component reaction of pyrrole with arylglyoxal derivatives and Meldrum’s acid (MA) in water at room temperature afforded 2,2-dimethyl-5- (2-oxo-2-aryl-1- (1H-pyrrol-2-yl) ethyl) -1,3-dioxane-4,6-dione derivatives under catalyst-free conditions in high yields. Products were isolated and purified by simple filtration and washing with diethyl ether and their structures were established from their IR and NMR spectroscopic data.
Damanzan, Z., Anary-Abbasinejad, M., & Masoudi, M. (2021). A Facile and Green Approach for One-Pot Synthesis of New Pyrrole Derivatives by Three-Component Reaction Between Pyrrole, Arylglyoxals and Meldrum's Acid. Organic Chemistry Research, 7(1), 86-91. doi: 10.22036/org.chem.2023.299025.1263
MLA
Zahra Damanzan; Mohammad Anary-Abbasinejad; Mozhgan Masoudi. "A Facile and Green Approach for One-Pot Synthesis of New Pyrrole Derivatives by Three-Component Reaction Between Pyrrole, Arylglyoxals and Meldrum's Acid". Organic Chemistry Research, 7, 1, 2021, 86-91. doi: 10.22036/org.chem.2023.299025.1263
HARVARD
Damanzan, Z., Anary-Abbasinejad, M., Masoudi, M. (2021). 'A Facile and Green Approach for One-Pot Synthesis of New Pyrrole Derivatives by Three-Component Reaction Between Pyrrole, Arylglyoxals and Meldrum's Acid', Organic Chemistry Research, 7(1), pp. 86-91. doi: 10.22036/org.chem.2023.299025.1263
VANCOUVER
Damanzan, Z., Anary-Abbasinejad, M., Masoudi, M. A Facile and Green Approach for One-Pot Synthesis of New Pyrrole Derivatives by Three-Component Reaction Between Pyrrole, Arylglyoxals and Meldrum's Acid. Organic Chemistry Research, 2021; 7(1): 86-91. doi: 10.22036/org.chem.2023.299025.1263
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