Ultrasound Promoted Efficient Synthesis of some Amides from Nitriles in Ambient Condition

Document Type : Full Paper


1 Vali-e-Asr University

2 Vali-e-Asr University of Rafsanjan


      Some amide derivatives have been synthesized by the reaction of corresponding nitriles with potassium tert-butoxide as a nucleophilic oxygen source under ultrasonic irradiation. This new methodology provides good to excellent yields in short reaction times (15-90 min) at room temperature.