Ultrasound-Promoted Synthesis of Aryl Amides from Isocyanides and Carboxylic Acids under Ambient Conditions

Document Type : Full Paper

Authors

1 Department of Chemistry, University of Zanjan, P O Box 45195-313, Zanjan, Iran

2 Young Researchers and Elite Club, Zanjan Branch, Islamic Azad University, Zanjan, Iran

3 School of Mechanical Engineering, Yeungnam University, Gyongsan 712-749, Korea

Abstract

The synthesis of aryl amides via the reactions of carboxylic acids and isocyanides in methanol was carried out in 78-95% yields under ultrasound irradiation. The method has wide applicability, and the protocol is mild, fast and efficient compared to the existing methods based on silent conditions.

Keywords

Organic Chemistry Research
Volume 1, Issue 1 - Serial Number 1
September 2015
Pages 12-17

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