%0 Journal Article %T Saccharomyces Cerevisiae as a Biocatalyst for Different Carbonyl Group under Green Condition %J Organic Chemistry Research %I Iranian Chemical Society %Z 2383-242X %A Motallebi, Sogol %A Mahmoodi, Nosrat o %A Ghanbari Pirbati, Fateme %A Azimi, Abbas %D 2016 %\ 03/01/2016 %V 2 %N 1 %P 39-42 %! Saccharomyces Cerevisiae as a Biocatalyst for Different Carbonyl Group under Green Condition %K Saccharomyces Cerevisiae %K Baker’s yeast %K Bio-reduction %K (3-(3-Nitrophenyl)aziridin-2-yl)-1-phenyl-methanone %K Pyruvate ester %K 2-Acetyl-γ-butyrolactone %R 10.22036/org.chem..2016.13076 %X In this researchsaccharomyces cerevisiae (baker’s yeast) was used as a cheap, readily accessible, selective, efficient, and green bio-catalyst in a chemo selective reduction of carbonyl group to hydroxyl group. In this green procedure three substrates e.g. (3-(3-nitrophenyl)aziridin-2-yl)-1-phenyl-methanone, pyruvate ester, and 2-acetyl-γ-butyrolactone were reduced to their corresponding reduced compounds in the presence of saccharomyces cerevisiae atambient temperature in aqueous media. It was worthy to note that ketone groups were chemo-selectively reduced, while ester and lactone groups remained unchanged. Moreover, in this procedure, chemo selective bio-reduction of ketone group to hydroxyl group can be performed by coenzyme NADPH in saccharomyces cerevisiae (baker’s yeast) which is recyclable in water, as a green solvent, while this recyclization cannot occur in non-aqueous systems. The structure of products was confirmed by IR and 1H NMR spectra. %U https://www.orgchemres.org/article_13076_5778989cc34fbed52d42a183d8405578.pdf