@article { author = {Niknam, Khodabakhsh and Hosseini, Alireza}, title = {Synthesis of 2-Amino-3,5-dicarbonitrile-6-thiopyridines Using Silica-bonded N-Propyldiethylenetriamine as a Heterogeneous Solid Base Catalyst}, journal = {Organic Chemistry Research}, volume = {3}, number = {1}, pages = {16-24}, year = {2017}, publisher = {Iranian Chemical Society}, issn = {2383-242X}, eissn = {2383-242X}, doi = {10.22036/org.chem..2017.41100}, abstract = {Silica-bonded N-propyldiethylenetriamine (7) is employed as a recyclable heterogeneous solid base catalyst for the synthesis of 2-amino-3,5-dicarbonitrile-6-thiopyridines through pseudo four-component condensation reaction between aromatic aldehydes, malononitrile, and 2-amino-thiophenol in refluxing ethanol. Silica-bonded N-propyldiethylenetriamine showed much the same efficiency when used in consecutive reaction runs.}, keywords = {2-Amino-3,5-dicarbonitrile-6-thiopyridines,Heterogeneous catalysts,Solid bases,Synthesis,Multi-component reactions}, url = {https://www.orgchemres.org/article_41100.html}, eprint = {https://www.orgchemres.org/article_41100_b8519134586b3bb79cb05f3aa49de9dd.pdf} }