Khosravi, K., Azizi, A., Naserifar, S. (2019). Efficient Oxidative Dehydrogenation of Dihydropyrimidinones and Thiocyanation of Aromatic Compounds Using 1,1,2,2-Tetrahydroperoxy-1,2-diphenylethane as the Oxidant. Organic Chemistry Research, 5(2), 128-138. doi: 10.22036/org.chem.2018.133843.1152
Kaveh Khosravi; Amir Azizi; Shirin Naserifar. "Efficient Oxidative Dehydrogenation of Dihydropyrimidinones and Thiocyanation of Aromatic Compounds Using 1,1,2,2-Tetrahydroperoxy-1,2-diphenylethane as the Oxidant". Organic Chemistry Research, 5, 2, 2019, 128-138. doi: 10.22036/org.chem.2018.133843.1152
Khosravi, K., Azizi, A., Naserifar, S. (2019). 'Efficient Oxidative Dehydrogenation of Dihydropyrimidinones and Thiocyanation of Aromatic Compounds Using 1,1,2,2-Tetrahydroperoxy-1,2-diphenylethane as the Oxidant', Organic Chemistry Research, 5(2), pp. 128-138. doi: 10.22036/org.chem.2018.133843.1152
Khosravi, K., Azizi, A., Naserifar, S. Efficient Oxidative Dehydrogenation of Dihydropyrimidinones and Thiocyanation of Aromatic Compounds Using 1,1,2,2-Tetrahydroperoxy-1,2-diphenylethane as the Oxidant. Organic Chemistry Research, 2019; 5(2): 128-138. doi: 10.22036/org.chem.2018.133843.1152
Efficient Oxidative Dehydrogenation of Dihydropyrimidinones and Thiocyanation of Aromatic Compounds Using 1,1,2,2-Tetrahydroperoxy-1,2-diphenylethane as the Oxidant
1Faculty of Science, Department of Chemistry, Arak University, Arak 38156-8-8349, Iran.
2Faculty of Science, Department of Chemistry, Arak University, Arak 38156-8-8349, Iran
Abstract
A new, efficient and mild approach for the oxidative dehydrogenation of dihydropyrimidinones and thiocyanation of aromatic compounds using 1,1,2,2-tetrahydroperoxy-1,2-diphenylethane (THPDPE) as a terminal oxidant was developed. Initially, various substrates bearing different electron-donating and electron-releasing functionalities were synthesized and next under the optimized reaction conditions the desired products were yielded after an easy work-up and the structures were characterized compared with those reported. All of the reactions proceeded in short reaction times and 1,1,2,2-tetrahydroperoxy-1,2-diphenylethane (THPDPE) proved its potential to yield the desired products in high yields.
