Document Type: Research Paper
University of Guilan
Department of Chemistry, Faculty of Sciences, University of Guilan
In this report a green strategy for the synthesis of polyhydroacridine derivatives via one-pot three-component coupling reaction of arylaldehydes, 1,3-cyclohexanedione and aniline derivatives in the presence of modified montmorillonite (Fe3+@mont.) as heterogeneous and reusable catalyst under solvent-free conditions was developed. The reaction in the presence of this catalyst furnished the desired products in short reaction times (10-15 min.) and high to excellent yields (78-98%).