Green Multicomponent Synthesis of Benzodiazepines in the Presence of CuFe2O4 as an Efficient Magnetically Recyclable Nanocatalyst under Solvent-Free Ball-Milling Conditions at Room Temperature
In this work, an efficient and green procedure for the synthesis of various substituted 1,5-benzodiazepine derivatives via a one-pot three-component catalytic reaction has been described. The reaction was conducted between o-phenylenediamine, dimedone and aldehyde derivatives in the presence of CuFe2O4 nanoparticles as a magnetic heterogeneous nanocatalyst under ball-milling conditions at room temperature. High yields of the products, short reaction times, simplicity of operation, mild reaction conditions, non-toxicity, easy work-up and purification of the products through crystallization method (chromatography-free) and recyclability of the catalyst are added advantages of this work.
Maleki, A., Firouzi-Haji, R., & Farahani, P. (2018). Green Multicomponent Synthesis of Benzodiazepines in the Presence of CuFe2O4 as an Efficient Magnetically Recyclable Nanocatalyst under Solvent-Free Ball-Milling Conditions at Room Temperature. Organic Chemistry Research, 4(1), 86-94. doi: 10.22036/org.chem.2018.96769.1106
MLA
Ali Maleki; Razieh Firouzi-Haji; Parisa Farahani. "Green Multicomponent Synthesis of Benzodiazepines in the Presence of CuFe2O4 as an Efficient Magnetically Recyclable Nanocatalyst under Solvent-Free Ball-Milling Conditions at Room Temperature". Organic Chemistry Research, 4, 1, 2018, 86-94. doi: 10.22036/org.chem.2018.96769.1106
HARVARD
Maleki, A., Firouzi-Haji, R., Farahani, P. (2018). 'Green Multicomponent Synthesis of Benzodiazepines in the Presence of CuFe2O4 as an Efficient Magnetically Recyclable Nanocatalyst under Solvent-Free Ball-Milling Conditions at Room Temperature', Organic Chemistry Research, 4(1), pp. 86-94. doi: 10.22036/org.chem.2018.96769.1106
VANCOUVER
Maleki, A., Firouzi-Haji, R., Farahani, P. Green Multicomponent Synthesis of Benzodiazepines in the Presence of CuFe2O4 as an Efficient Magnetically Recyclable Nanocatalyst under Solvent-Free Ball-Milling Conditions at Room Temperature. Organic Chemistry Research, 2018; 4(1): 86-94. doi: 10.22036/org.chem.2018.96769.1106