SbCl3 as an Efficient Catalyst for the One-pot Synthesis of Highly Substituted Piperidines

Document Type: Research Paper

Authors

1 University of Sistan and Baluchestan

2 University of Sistan and Baluchestan, Zahedan, Iran

3 Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box: 98135-674, Zahedan, Iran

Abstract

Highly substituted piperidines were synthesized via the condensation of aromatic aldehydes and aromatic amines with β-ketoesters in the presence of antimony(III) chloride at ambient condition. This reaction has any advantages such as easy work-up, clean procedure, and good yields.

Keywords