Document Type: Research Paper
Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674 Zahedan, Iran
Chemistry department of, The University of Sistan and Baluchestan, P. O. Box 98135-674, Zahedan, Iran
A very efficient one-pot three-component synthesis of pyran derivatives has been improved by condensation of aldehydes and malononitrile with dimedone under 80 °C using sucrose as natural and biodegradable catalyst in water. This method offers some advantages including inexpensive, high to quantitative yields, short reaction time, and easy work-up. Therefore, this methodology is entirely green and environmentally benign protocol for the preparation of tetrahydrobenzo[b]pyran derivatives.