2024-03-28T13:30:37Z
https://www.orgchemres.org/?_action=export&rf=summon&issue=10355
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
Tonsil Clay as a Green Catalyst for Rapid and Efficient Reduction of Aldehydes and Ketones with NaBH3CN
Ali
Danesh
Masomeh
Aghazadeh
Mohammad
Jalilzadeh Hedayati
Reduction of aldehydes and ketones to the corresponding alcohols in the presence of sodium cyanoborohdride as reductive agent and Tonsil clay as catalyst under solvent free conditions was investigated. Tonsil (catalyst) decreased the reduction time of each aldehyde and ketone to proportional alcohols in comparison with their reduction in the absence of catalyst with high degree purity of alcohols. Reduction reactions were carried out in solvent free condition in less than 15 minutes at room temperature. All obtained alcohols from reduction of related carbonyl compounds were detected by FT-IR and 1H/13C NMR spectra.
Sodium cyanoborohydride
Tonsil clay
reduction
Aldehyde
Ketone
Alcohols
Green chemistry
2019
12
01
112
116
https://www.orgchemres.org/article_81516_679c5c97ef214a9b264c5b482113efcf.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
La(OTf)2-amine Grafted-GO as the First Multifunctional Catalyst for the One-pot Three-component Synthesis of α-Aminophosphonates
Sara
Sobhani
Farzaneh
Zarifi
Farshid
Barani
Jorgen
Skibsted
In this paper, the applicability of immobilized lanthanum (III) triflate on amine grafted graphene oxide [La(OTf)2-amine grafted-GO] as the first multifunctional catalyst is described for the efficient synthesis of α-aminophosphonates by one-pot three-component reaction of carbonyl compounds, substituted anilines and trialkyl phosphites. Various α-aminophosphonates were synthesized in good to high yields under solvent-free conditions at room temperature. The catalyst was reused five times without significant loss of its activity.
Multifunctional catalyst
One-pot reaction
α-Aminophosphonates
Kabachnik-Fields reaction
2019
12
01
117
127
https://www.orgchemres.org/article_81518_7e99032d4f26a19756c5d4c539c1313c.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
Efficient Oxidative Dehydrogenation of Dihydropyrimidinones and Thiocyanation of Aromatic Compounds Using 1,1,2,2-Tetrahydroperoxy-1,2-diphenylethane as the Oxidant
Kaveh
Khosravi
Amir
Azizi
Shirin
Naserifar
A new, efficient and mild approach for the oxidative dehydrogenation of dihydropyrimidinones and thiocyanation of aromatic compounds using 1,1,2,2-tetrahydroperoxy-1,2-diphenylethane (THPDPE) as a terminal oxidant was developed. Initially, various substrates bearing different electron-donating and electron-releasing functionalities were synthesized and next under the optimized reaction conditions the desired products were yielded after an easy work-up and the structures were characterized compared with those reported. All of the reactions proceeded in short reaction times and 1,1,2,2-tetrahydroperoxy-1,2-diphenylethane (THPDPE) proved its potential to yield the desired products in high yields.
Dehydropirimidinones
Oxidative dehydrogenation
Thiocyanation
1
2
2-Tetrahydroperoxy-1
2-diphenylethane
Pyrimidinones
2019
12
01
128
138
https://www.orgchemres.org/article_82180_3f347196f65302cd4bd10875929e7a5f.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
One-pot Four-component Reaction between Arylamines, Arylglyoxals, Cyclohexyl Isocyanide, and Acetylene Diesters: An Efficient Synthesis of 2H-iminopyran Derivatives
Mohammad
Anary-Abbasinejad
Maryam
Jaafari
Mahdiyeh
Talebizadeh
A facile synthesis of highly functionalized 2H-iminopyran derivatives by the multi-component reaction of cyclohexyl isocyanide, dialkyl acetylenedicarboxylates, arylglyoxals and arylamines is described. The zwitterionic intermediate produced by addition of cyclohexyl isocyanide to electron-deficient acetylene diesters was trapped by the electrophilic imine moiety of α-iminoketones, derived from arylglyoxals and arylamines, to afford an inner salt intermediate which converted to 2H-iminopyran derivatives by an intramolecular cyclization.
α-Iminoketones
Isocyanide
Iminopyrans
Four-component reaction
Arylglyoxals
2019
12
01
139
144
https://www.orgchemres.org/article_82413_8a53b4049d01c25cde499f8d1f9c597d.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
N1,N1,N2,N2-tetramethyl-N1,N2-bis(sulfo)ethane-1,2-diaminium Chloride ([TMBSED][Cl]2): An Efficient Ionic Liquid Catalyst for the One-pot Synthesis of Dihydropyrrol-2-ones and Tetrahydropyridines
Seyed Sajad
Sajadikhah
Abdolkarim
Zare
Narges
Hosseini
N1,N1,N2,N2-tetramethyl-N1,N2-bis(sulfo)ethane-1,2-diaminium chloride ([TMBSED][Cl]2) was synthesized as an acidic ionic liquid and characterized using FT-IR, 1H and 13C NMR, mass spectroscopy, TG, DTG and DTA techniques. This ionic liquid was employed as efficient catalyst for the extremely facile and efficient synthesis of dihydropyrrol-2-ones and functionalized tetrahydropyridines. One-pot four-component reaction of amines, dialkyl acetylenedicarboxylates and formaldehyde in the presence of [TMBSED][Cl]2 in ethanol at ambient temperature provides substituted dihydropyrrol-2-ones in good to high yields. This ionic liquid catalyst was also found useful for the synthesis of functionalized tetrahydropyridines using a multi-component reaction of amines, aldehydes and β-ketoesters in methanol.
Dihydropyrrol-2-one
Tetrahydropyridine
Multi-component reaction
Ionic Liquid
[TMBSED][Cl]2
2019
12
01
145
158
https://www.orgchemres.org/article_82414_f3644a90a2b99e4674b1701100146f06.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
Four-component Cascade Reaction was Programmed and Catalyzed by B(OH)3.H2O as an Efficient and Green Catalytic System
Ahmad Reza
Moosavi-Zare
Hadis
Afshar-Hezarkhani
Vahid
Khakizadeh
Hamid
Goudarziafshar
An aqueous solution of boric acid, as an efficient and green catalytic system, was efficiently utilized four-component cascade reaction of aryl aldehydes, dimedone, β-ketoesters and ammonium acetate to give hexahydroquinolines. By the reaction of boric acid with water, H+ was generated and efficiently catalyzed the reaction under mild and green condition. Also, optimization of the reaction condition was investigated using the response surface method {Central Composite Design (CCD)}.
Boric acid
Hexahydroquinoline
Cascade reaction
Aqueous solution
2019
12
01
159
166
https://www.orgchemres.org/article_82601_dba73d95ef80a65595e7f93a832684eb.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
One-pot Synthesis of Pyrono [2,3] Quinoline via the Tandem Cyclization of Algar-Flyn-Oyamanda Reactions
Nepolraj
Amaladoss
Pitchai
Pandian
Mani
Panagal
A new and imaginative technique for the synthesis of substituted pyranoquinoline via Algar Flyn Oyamanda oxidation cyclization approach has been achieved by hydrogen peroxide and sodium hydroxide catalyzed of quinoline chalcone with intramolecular cyclization to formed pyranoquinoline. In this reaction, two new C-C bonds were formed in a one step with high atom economy. The possible reaction pathway for the formation of the products was also discussed in greener technique this paper.
Algar-Flyn-Oyamanda oxidation
Pyranoquinoline
Intramolecular cyclization
Greener technique
2019
12
01
167
173
https://www.orgchemres.org/article_82649_0a2122c7da5672d3ab092962d89c8f89.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
Nano Silica Melamine Trisulfonic Acid as an Efficient and Reusable Heterogeneous Catalyst for the Synthesis of 5-Substituted-1H-Tetrazoles
P.
Movaheditabar
Mohammad
Javaherian
A convenient method for the synthesis of 5-substituted-1H-tetrazoles from organic nitriles and sodium azide in the presence of nano silica melamine trisulfonic acid is reported. A series of aliphatic and aromatic nitriles were underwent a [3+2] cycloaddtion with sodium azide to afford tetrazoles in good to excellent yields and acceptable reaction times. The nano silica melamine trisulfonic acid is an efficient heterogeneous nanocatalyst with high catalytic performance. The nano silica melamine trisulfonic acid is readily prepared, environmentally friendly and reusable. The catalyst was characterized by Powder X-ray diffraction, energy-dispersive X-ray mapping and SEM techniques. The procedure was simple, cost effective that holds potential for further applications in organic syntheses and industrial requirements.
Nano silica melamine trisulfonic acid
tetrazole
Heterogeneous nanocatalyst
Cycloaddition
Sodium azide
2019
12
01
174
189
https://www.orgchemres.org/article_85318_1d0922bd29f61b0b66bc70f18e38a44f.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
Green Synthesis of Silver and Magnetite Nanoparticles Using Cleome Heratensis (Capparaceae) Plant Extract
Mohammadali
Nasseri
Soheila
Behravesh
Ali
Allahresani
Milad
Kazemnejadi
In the recent decades, development of green and reliable processes for synthesis of metallic nanoparticles is inevitable because of their important applications in all fields of science, especially in nanotechnology and industry. Biological systems have received great attentions from scientist due to low cat, green nature and simple process for synthesis of metallic NPs. In this research, metal nanoparticles, Ag and Fe3O4 NPs, were synthesized through an ecofriendly and cost effective approach using aqueous extract of Cleome heratensis (C. heratensis). The influence of effective parameters including pH, interaction time, temperature, plant extract concentration and Ag concentration were thoroughly investigated base on surface plasmon resonance (SPR) for Ag NPs at max 470 nm. The bio-synthesized NPs were characterized by FTIR, UV-Vis, XRD, TEM and VSM analyses. The TEM images showed the size of silver and magnetite nanoparticles as 12.27 and 14.12 nm respectively with a homogeneous distribution and nearly spherical in shape.
C. heratensis
Capparaceae
Bio-synthesis
Silver nanoparticles
Magnetite nanoparticles
2019
12
01
190
201
https://www.orgchemres.org/article_87927_e48254af7fc867919673442e3c4c7c0e.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
Reaction of Poly (Propylene Imine) Dendrimer with Carboxylated Amines
Sabah
Salahvarzi
Shabnam
Shamaie
Abstract In this research, new derivatives of poly (propylene imine) dendrimer were synthesized using propylamine and ethylenediamine. First, amines via aza-Micheal addition reacted with methyl acrylate, then their products were affected treated with poly (propylene imine) dendrimer (PPI). The products were identified by FT- IR, 1 HNMR and 13CNMR methods. Morphology and size of particles were evaluated by scanning electron microscopy.
Propylamine
Ethylenediamine
Aza-Micheal addition reaction
Poly (propylene imine) dendrimer
2019
12
01
202
223
https://www.orgchemres.org/article_88241_2ec38b11cef046caf96890b175734234.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
L-Cysteine-functionalized ZnS Nanoparticles as a Catalyst for the Synthesis of β-amino Carbonyl Compound via MCR Mannich Reaction
Narjes
Alamolhodaei
Hossein
Eshghi
Hossein
Massoudi
Three components one-pot Mannich reaction of ketone, aromatic aldehyde and aromatic amines has been efficiently catalyzed by recyclable and heterogeneous L-Cysteine supported on ZnS nanoparticles at ambient temperature to give various β-amino carbonyl compounds with high yields. This simple method has some advantages such as mild condition and no environmental pollution. Structures of the compounds were confirmed by 1H NMR and IR spectral analyses. ZnS nanoparticles were prepared in hydrothermal procedure from an aqueous solution of Zinc acetate and NaS in the presence of L-Cysteine. L-Cysteine supported on ZnS nanoparticles was characterized by FT-IR, TEM, TGA/DTA and XRD analysis.
Mannich
L-cysteine
Functionalized ZnS
β-amino carbonyl
2019
12
01
224
232
https://www.orgchemres.org/article_88242_70379fa5307f7fe9990bfc4e01241e1f.pdf
Organic Chemistry Research
Org. Chem. Res.
2019
5
2
Synthesis of Poly-substituted Hydroquinolines Employing Lactic Acid as a Robust Catalyst through the Diastereoselective, One-pot Eight-component Reaction
Fatemeh
Noori Sadeh
Mojtaba
Lashkari
Nourallah
Hazeri
Maryam
Fatahpour
Malek Taher
Maghsoodlou
With the aim of developing an efficient and eco-friendly method for a diastereoselective synthesis of dispiro[tetrahydroquinoline-bis(2,2-dimethyl[1,3] dioxane-4,6-dione)] derivatives, a one-pot pseudo-eight-components reaction between arylamines, aromatic aldehydes and Meldrum’s acid has occurred in the presence of lactic acid as catalyst. The salient aspects of this protocol are, operational simplicity, facile product separation, a cheap and eco-friendly catalyst, clean reaction conditions, absence of any hazardous organic solvent and moderate to high yields.
Diastereoselective
Dispiro[tetrahydroquinoline-bis(2
2-dimethyl[1
3] dioxane-4
6-dione)]
Pseudo-eight-components reaction
Meldrum’s acid
Lactic acid
2019
12
01
233
240
https://www.orgchemres.org/article_88272_aa90ce8aa4799785d9ce156f81cea947.pdf