TY - JOUR ID - 13076 TI - Saccharomyces Cerevisiae as a Biocatalyst for Different Carbonyl Group under Green Condition JO - Organic Chemistry Research JA - ORG.CHEM LA - en SN - AU - Motallebi, Sogol AU - Mahmoodi, Nosrat o AU - Ghanbari Pirbati, Fateme AU - Azimi, Abbas AD - PhD Student - Chemical engineering AD - corresponding Faculty of Sciences, University of Guilan, Rasht, Guilan, Iran, AD - Faculty of Sciences, University of Guilan, Rasht, Iran AD - Faculty of Sciences, University of Guilan, Rasht, Iran. Y1 - 2016 PY - 2016 VL - 2 IS - 1 SP - 39 EP - 42 KW - Saccharomyces Cerevisiae KW - Baker’s yeast KW - Bio-reduction KW - (3-(3-Nitrophenyl)aziridin-2-yl)-1-phenyl-methanone KW - Pyruvate ester KW - 2-Acetyl-γ-butyrolactone DO - 10.22036/org.chem..2016.13076 N2 - In this researchsaccharomyces cerevisiae (baker’s yeast) was used as a cheap, readily accessible, selective, efficient, and green bio-catalyst in a chemo selective reduction of carbonyl group to hydroxyl group. In this green procedure three substrates e.g. (3-(3-nitrophenyl)aziridin-2-yl)-1-phenyl-methanone, pyruvate ester, and 2-acetyl-γ-butyrolactone were reduced to their corresponding reduced compounds in the presence of saccharomyces cerevisiae atambient temperature in aqueous media. It was worthy to note that ketone groups were chemo-selectively reduced, while ester and lactone groups remained unchanged. Moreover, in this procedure, chemo selective bio-reduction of ketone group to hydroxyl group can be performed by coenzyme NADPH in saccharomyces cerevisiae (baker’s yeast) which is recyclable in water, as a green solvent, while this recyclization cannot occur in non-aqueous systems. The structure of products was confirmed by IR and 1H NMR spectra. UR - https://www.orgchemres.org/article_13076.html L1 - https://www.orgchemres.org/article_13076_5778989cc34fbed52d42a183d8405578.pdf ER -