eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
1
10
10.22036/org.chem.2017.94388.1099
55278
Ultrasound-promoted Catalyst-free Synthesis of α-Aminonitriles in 1-Butyl-3-methylimidazolium Bromide ([Bmim]Br) as a Reusable Neutral Ionic Liquid
Mohsen Shekouhy
m.shekouhy@gmail.com
1
Reza Kordnezhadian
rezakd8835@gmail.com
2
Ali Khalafi-Nezhad
khalafi@chem.susc.ac.ir
3
Department of Chemistry, College of Sciences, Shiraz University, Shiraz, Iran
Department of Chemistry, College of Sciences, Shiraz University, Shiraz, Iran
Department of Chemistry, College of Sciences, Shiraz University, Shiraz, Iran
A catalyst-free one-pot three component methodology for the synthesis of α-aminonitriles under ultrasonic irradiation at room temperature using [Bmim]Br as a neutral reaction medium is described. A broad range of substrates including the aromatic, heteroaromatic and aliphatic aldehydes were condensed with amines (aliphatic and aromatic) and trimethylsilyl cyanide (TMSCN). Using this method, all reactions were completed in short times and the products were obtained in good to excellent yields. The reaction medium could be recycled and reused several times without any loss of efficiency.
https://www.orgchemres.org/article_55278_2bcbe0cb3dec6ede5ea1e7079b6109ae.pdf
α-Aminonitrile
1-Butyl-3-methylimidazolium bromide
Catalyst-free synthesis
Ultrasound-promoted synthesis
Ionic Liquid
Green chemistry
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
11
22
10.22036/org.chem.2017.95828.1102
55279
Efficient Synthesis of Benzo[b]pyrans and Knoevenagel Products Using Magnetically Separable Nano TPPA-IL-Fe3O4
Arash Ghorbani-Choghamarani
arashghch58@yahoo.com
1
Mohsen Nikoorazm
e_nikoorazm@yahoo.com
2
Masoomeh Norouzi
norouzi_88organic@yahoo.com
3
ilam university
Ilam University
Ilam University
A simple, efficient, and green practical approach to Knoevenagel condensation of malononitrile and different aldehydes has been developed using an ionic liquid functionalized on Fe3O4 magnetic nanoparticles as heterogeneous catalyst. This nanostructural catalyst has also been applied for the synthesis of 4H-benzo[b]pyran derivatives in water at room temperature in short reaction time. All of the products were obtained in good to excellent yields. The TPPA-IL-Fe3O4 catalyst was used at least seven times with comparable activities to the fresh catalyst.
https://www.orgchemres.org/article_55279_8fbf4f0a5deb6c39c971fac92a91f7b6.pdf
Ionic Liquid
Fe3O4 magnetic nanoparticles
Knoevenagel condensation
4H-benzo[b]pyran
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
23
42
10.22036/org.chem.2017.96890.1108
55280
Efficient Synthesis of Nickel(II) Complex Supported on Fe3O4@SiO2 Nanoparticles as a New and Facile Catalyst for Various Multicomponent Reactions
Maryam Hajjami
mhajjami@yahoo.com
1
Razieh Nejat
sahba_r_nejat@yahoo.com
2
Fatemeh Sharifirad
f.sharifirad72@yahoo.com
3
Fatemeh Gholamian
fgholamyan@yahoo.com
4
department of chemistry, faculty of science, ilam university, ilam, iran
bDepartment of Chemistry, Faculty of science, Kosar university of Bojnord, P.O. Box 9415615458 Bojnord
Department of Chemistry, Faculty of Science, Ilam University, P.O. Box 69315516, Ilam, Iran
Department of Chemistry, Faculty of Science, Ilam University, P.O. Box 69315516, Ilam, Iran
In the present work, we have planned a new magnetically recoverable nanocatalyst. The obtained nanocatalyst designated as Fe3O4@SiO2@DOPisatin-Ni (II) was characterized by FTIR, XRD, SEM, EDAX, VSM, AAS and TGA techniques. It was found that Fe3O4@SiO2@DOPisatin-Ni (II) successfully catalyses the synthesis of 2,3-dihydroquinazolin-4(1H)-ones, polyhydroquinoline and 5-substituted 1H-tetrazoles in solvent free condition and PEG as a green solvent.
https://www.orgchemres.org/article_55280_4e576d237e8b4354df96daa09b904f8b.pdf
Magnetically nickel(II)
2
3-Dihydroquinazolin-4(1H)-ones
Polyhydroquinoline
5-Substituted 1H-tetrazoles
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
43
57
10.22036/org.chem.2017.95441.1100
55957
Design of Palladium(II) Chloride-supported-N-(dipyridine-2-ylmethyl)-3-(silica- magnetite)propan-1-amine and its Application on the Cross-coupling
Mahmoud Zarei
mahmoud8103@yahoo.com
1
Mohammadali Zolfigol
mzolfigol@yahoo.com
2
Ahmad Reza Moosavi-Zare
moosavizare@yahoo.com
3
Ehsan Noroozizadeh
ehsannoroozizadeh3163@gmail.com
4
Depatment of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683
Depatment of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683
Department of Chemistry, University of Sayyed Jamaleddin Asadabadi, Asadabad 6541835583, Iran
Depatment of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683,
In this work, palladium (II) chloride-supported-N-(dipyridine-2-ylmethyl)-3-(silica-magnetite)propan-1-amine (nano-Fe3O4@SiO2@dipy@PdCl2) as a new nanostructured catalyst was prepared and its structure completely studied by different techniques and then successfully tested on Heck and Suzuki reactions.
https://www.orgchemres.org/article_55957_839ab03d693ff228776eafcefa8e0813.pdf
Nano-Fe3O4@SiO2@dipy@PdCl2
Nano magnetic Fe3O4
Cross coupling reaction
Heck reaction
Suzuki reaction
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
58
66
10.22036/org.chem.2017.97958.1112
56133
Ammonium-type Basic Ionic Liquid; 2-(2-Hydroxyethoxy)ethaneammonium Formate: Promote Green and Efficient Multicomponent Tandem Synthesis of 4H-pyrans and 4H-chromenes
Kamal Amani
amani_71454@yahoo.com
1
Maisam Yarie
myari.5266@yahoo.com
2
Fomida Shahbazi
fomeida.shahbazi@yahoo.com
3
Department of Chemistry, Faculty of Sciences, University Of Kurdistan, Sanandaj, Iran
Department of Chemistry, College of Science, University of Kurdistan, Sanandaj 66177-15143, Iran
University of Kurdistan
A facile, convenient, green and environmentally benign one-pot three-component synthesis of poly-functionalized 4H-pyrans and 4H-chromenes is described. A basic ionic liquid 2-(2-hydroxyethoxy)ethaneammonium formate was found to be an efficient catalyst or catalytically active solvent for the synthesis of those important classes of heterocyclic compounds.
https://www.orgchemres.org/article_56133_9a8b143ed5ca9e100eeac6fcbd9f4524.pdf
4H-pyran
4H-chromene
Basic ionic liquid
2-(2-Hydroxyethoxy)ethaneammonium formate
One-pot three-component synthesis
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
67
72
10.22036/org.chem.2017.92847.1098
56134
Ultrasonic-assisted Synthetic Improvement of Fluorinated Five- and Six-membered Triazolotriazine and Triazinophthalazine Heterocycles
Ali Darehkordi
darehkordi@vru.ac.ir
1
Mahin Ramezani
mahinramezani14@gmail.com
2
Department of Chemistry
Vali-e-Asr University of Rafsanjan
Rafsanjan
Iran
Department of Chemistry Vali-e-Asr University of Rafsanjan Rafsanjan Iran
In this investigation a simple synthetic method for the synthesis of trifluoromethyl-1H-benzo[e][1,2,4]triazolo[1,2-a][1,2,4]triazine-1,3(2H)-diones and (trifluoromethyl)benzo [5,6][1,2,4]triazino[1,2-b]phthalazine-8,13-diones has been developed using urazole or phthalazine and aceteimidoyl chloride derivatives at room temperature under ultrasound irradiations. In the comparison to the conventional method the ultrasound irradiation increased the yield and the reactions times decreased considerably.
https://www.orgchemres.org/article_56134_397afc836af5f6a1a07bd8beca124d65.pdf
Ultrasound irradiation
Trifluoroacetimidoyl chloride
Urazole
Phthalazine
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
73
85
10.22036/org.chem.2017.98634.1113
57330
Fe3O4@SiO2@Propyl-ANDSA: A New Catalyst for the Synthesis of Substituted Pyrroles
Ramin Ghorbani-Vaghei
rgvaghei@yahoo.com
1
Hassan Sanati
2
Sedigheh Alavinia
3
Bu-Ali Sina University
Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, 6517838683, Iran
Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, 6517838683, Iran
Substituted pyrroles are an essential class of heterocyclic compounds. In this research, an efficient and eco-friendly method has been developed for the synthesis of pyrrole derivatives from the reaction of 2,5-hexanedione and primary amines. Magnetic nanoparticles supported on functionalized. 7-aminonaphthalene-1,3-disulfonic acid-functionalized. silica (Fe3O4@SiO2@Propyl–ANDSA) has been investigated as a novel catalyst in this reaction. Herein, a novel catalyst was developed for an efficient and environmentally friendly synthesis of pyrrole in excellent yields. It should also be noted that Fe3O4@SiO2@Propyl–ANDSA as reaction catalyst could be recovered quickly and reused for several times without any decrease in efficiency. With its operational simplicity, green nature, and high yields the reaction will be acting as an attractive alternative for the synthesis of substituted pyrroles.
https://www.orgchemres.org/article_57330_538165dc6dc70a3730735e25590a917d.pdf
Fe3O4@SiO2@Propyl-ANDSA
Heterocyclic compounds
Pyrroles
Functionalized silica
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
86
94
10.22036/org.chem.2018.96769.1106
57776
Green Multicomponent Synthesis of Benzodiazepines in the Presence of CuFe2O4 as an Efficient Magnetically Recyclable Nanocatalyst under Solvent-Free Ball-Milling Conditions at Room Temperature
Ali Maleki
maleki@iust.ac.ir
1
Razieh Firouzi-Haji
2
Parisa Farahani
3
Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran
Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran
Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran
In this work, an efficient and green procedure for the synthesis of various substituted 1,5-benzodiazepine derivatives via a one-pot three-component catalytic reaction has been described. The reaction was conducted between o-phenylenediamine, dimedone and aldehyde derivatives in the presence of CuFe2O4 nanoparticles as a magnetic heterogeneous nanocatalyst under ball-milling conditions at room temperature. High yields of the products, short reaction times, simplicity of operation, mild reaction conditions, non-toxicity, easy work-up and purification of the products through crystallization method (chromatography-free) and recyclability of the catalyst are added advantages of this work.
https://www.orgchemres.org/article_57776_0ab27c4964942d598b7c9a236671adb4.pdf
Multicomponent reactions
Benzodiazepine
Magnetic heterogeneous nanocatalyst
CuFe2O4
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
95
99
10.22036/org.chem.2017.96614.1105
57777
One-pot Synthesis of Some Novel 2-[(Z)-1-(Aryl)]-6,7-dihydro-2H-istohiazolo[2,3-a]pyrimidine-3(5H)-one Derivatives
Akbar Mobinikhaledi
akbar_mobini@yahoo.com
1
Naser Foroughifar
n_foroughifar@yahoo.com
2
Hassan Moghanian
moghanian@gmail.com
3
Hamid Reza Jaberi
r_jaberi@yahoo.com
4
Chemistry Department, Arak University, Dr. Beheshti Ave, Arak, Iran
Faculty of Chemistry, Tehran North Branch, Islamic Azad University, Tehran, Iran
Department of Chemistry, Islamic Azad University-Dezful Branch, Dezful, Iran.
Department of Chemistry, Faculty of Science, Arak University, Arak, Iran
Reaction of 3,4,5,6-tetrahydro-2-pyrimidinethiol, prepared by cyclocondensation reaction of 1,3-diamino propane 1 and carbon disulfide, with ethyl chloroacetate and substituted aromatic aldehydes in the presence of sodium acetate and acetic acid gave 2-[(Z)-1-(aryl)]-6,7-dihydro-2H-isothiazolo[2,3-a]pyrimidine-3(5H)-one derivatives 3(a-j) in good yields. 1H-NMR spectroscopy, and elemental analysis were used for identification of these compounds.
https://www.orgchemres.org/article_57777_bfb642af3bedd7da30bd39a3e86c9aca.pdf
Condensation
Pyrimidine
Isothiazole
Synthesis
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
100
109
10.22036/org.chem.2018.102740.1116
61422
Polystyrene Supported [N-(Alanine) Sulfonamide]/Palladium Chloride: Synthesis, Characterization, for Heck Coupling Reactions
Parvaneh Shfieyoon
1
Ebrahim Mehdipour
e_mehdipour@yahoo.com
2
Department of Chemistry Faculty of Science Lorestan University, 68137-17133 Khorramabad Iran
Department of Chemistry Faculty of Science Lorestan University, 68137-17133 Khorramabad Iran
Abstract As a monomer, the [N-(alanine)] para-styrene sulfonamide (ASS) was prepared, from the reaction of para-styrene sulfonyl chloride and (S)-(+)-alanine in the presence of KOH 1M as a base, and CH3Cl was used as solvent. The monomer confirmed using FT-IR and 1H-NMR spectroscopy. Polystyrene [N-(alanine) sulfonamide] (PASS) was also prepared from the polymerization of [N-(alanine)] para-styrene sulfonamide (ASS) in the presence of AIBN (azoisobutyronitrile) under atmosphere of nitrogen. Then, the Polystyrene [N-(alanine) sulfonamide]/ palladium chloride as a polymer- supported palladium complex was also prepared from the reaction of PdCl2 (CH3CN)2 with PASS in the presence of KOH 1M. In the result, a green solid was appeared. Moreover, this catalyst was synthesized for the first time as a polymer-supported palladium and applied in Heck reactions.
https://www.orgchemres.org/article_61422_64f6fd278a8910baeb8d64cd9f0e3f34.pdf
[N-(Alanine)] para-styrene sulfonamide
Polystyrene [N-(alanine) sulfonamide]
Poly styrene [N-(alanine) sulfonamide]/ palladium chloride
Polymer-supported palladium
Heck reaction
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
110
115
10.22036/org.chem.2018.60464.1077
61898
Application of Ytterium Iron Garnet as a Powerful and Recyclable Nanocatalyst for the One-pot Synthesis of Octahydroquinazoline Derivatives under Solvent-free Conditions
Elham Sedighinia
esedighinia@gmail.com
1
Rashid Badri
esedighinia@yahoo.com
2
Alireza Kiasat
akiasat@scu.ac.ir
3
Department of Chemistry,Khouzestan Science and Research Branch
Department of Chemistry,Khouzestan Science and Research Branch
Chemistry Department, College of Science, Shahid Chamran
In this work, preparation and crystallization of yttrium iron garnet Y3Fe5O12 super-paramagnetic nanoparticle by aqueous sol–gel processes and its application as an effective nano catalyst for esterification and etherification reactions in short reaction time and in high isolated yields. Then this catalist was used for the synthesis of Dihydropyrimidin derivatives is described. The catalyst was identified by FT-IR spectroscopy, scanning electron microscopy (SEM), Transmission electron microscopy (TEM) , X-ray diffraction (XRD) , vibrating sample magnetometer(VSM) analysis.
https://www.orgchemres.org/article_61898_c32a3217913068b78f4b64208a8e10f6.pdf
Nanoparticle
Vtterium iron garnet
Octahydroquinazoline
Bijinelly
Sol-Gel
eng
Iranian Chemical Society
Organic Chemistry Research
2383-242X
2018-05-01
4
1
116
123
10.22036/org.chem.2018.97284.1110
63102
CuCr2O4 Nanoparticles: An Efficient Heterogeneous Catalyst for the Synthesis of Bis-thiazolidinones
Hossein Shahbazi-Alavi
hosseinshahbazi99@yahoo.com
1
Javad Safaei-Ghomi
safaeikashanu@yahoo.com
2
Seyed Hadi Nazemzadeh
shnazem@gmail.com
3
a Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, P.O. Box 87317-51167, I. R. Iran
bYoung Researchers and Elites Club, Kashan Branch, Islamic Azad University, Kashan, Iran
Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, P.O. Box 87317-51167, I. R. Iran
Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, P.O. Box 87317-51167, I. R. Iran
The preparation of bis-thiazolidinones has been achieved by a one-pot condensation reaction of araldehydes, ethylenediamine and thioglycolic acid in the presence of nano-CuCr2O4 nanoparticles under reflux conditions in toluene. This method provides several advantages including easy workup, excellent yields, short reaction times, reusability of the catalyst and low catalyst loading.
https://www.orgchemres.org/article_63102_c465fef08523eb971afe685feb1afb3f.pdf
CuCr2O4 nanoparticles
Bis-thiazolidinones
Ethylenediamine
One-pot
Thioglycolic Acid