@article { author = {Yazdani, Elahe and Azizi, Kobra and Nakisa, Athar and Heydari*, Akbar}, title = {Boric Acid-Functionalized Fe3O4@SiO2 as a Novel Superparamagnetically Recoverable Nano Catalyst for Mukaiyama-Aldol Reaction}, journal = {Organic Chemistry Research}, volume = {1}, number = {1}, pages = {27-36}, year = {2015}, publisher = {Iranian Chemical Society}, issn = {2383-242X}, eissn = {2383-242X}, doi = {10.22036/org.chem..2015.10661}, abstract = {We have reported the fabrication of boric acid incorporated into surface of magnetite nanoparticles. The catalyst was characterized using spectroscopic, magnetic and thermal techniques (FT-IR, SEM, XRD, ICP, VSM and TGA). It catalyzed Mukaiyama aldol reaction of a ketene silyl acetal type nucleophile ((1-methoxy-2-methylprop-1-enyloxy) trimethylsilane), and various aldehydes (aromatic, aliphatic, α,β-unsaturated), in acetonitrile and the yields were in the range of 45-98%. Magnetic Fe3O4-boric acid was multi-functional. The Fe3O4 core of the catalyst made easy separation and recycling while its boric acid portion catalyzed Mukaiyama aldol reaction. Nano size nature of the catalyst increased its activity in a way that boric acid, which is a weak Lewis acid, functioned similar to a more strong one like BF3. Boric acid functionality had the advantage of being moisture insensitive, economically reasonable and environmentally friendly. Furthermore Fe3O4@ SiO2@Boric acid was magnetically recovered via an external permanent magnet and was reused at least 6 times with a negligible change in its activity.}, keywords = {Mukaiyama,Boric acid,Magnetic catalyst}, url = {https://www.orgchemres.org/article_10661.html}, eprint = {https://www.orgchemres.org/article_10661_8c671af57192b8395129b0603734be58.pdf} }